Daular Sasaniya , wacce Ardashir I ya kafa, ta kasance fitacciyar iko sama da shekaru 400, tana adawa da Daular Rumawa daga baya.A kololuwarta, ta shafi Iran ta zamani, Iraki , Azerbaijan , Armeniya , Jojiya , wasu sassan Rasha, Lebanon, Jordan, Palasdinu, Isra'ila , sassan Afghanistan , Turkiyya , Siriya, Pakistan , Asiya ta Tsakiya, Larabawa ta Gabas, da wasu sassanMasar .^[27]Tarihin daular ya kasance mai yawan yaƙe-yaƙe tare da Daular Rumawa, ci gaban yakin Roman-Parthan.Waɗannan yaƙe-yaƙe, waɗanda suka fara a ƙarni na 1 KZ kuma suna dawwama har zuwa ƙarni na 7 AD, ana ɗaukar tashe-tashen hankula mafi dadewa a tarihin ɗan adam.Babban nasara ga Farisa ita ce a yakin Edessa a shekara ta 260, inda aka kama Sarkin sarakuna Valerian.A karkashin Khosrow II (590-628), daular ta fadada, ta hade Masar, Jordan, Falasdinu, da Lebanon, kuma an san shi da Erânshahr ("Mallakan Aryans").^[28] Sasaniyawa sun yi arangama da sojojin Romano-Byzantine akan Anatolia, Caucasus, Mesopotamiya, Armenia, da Levant.An kafa zaman lafiya a ƙarƙashin Justinian I ta hanyar biyan haraji.Duk da haka, rikice-rikice sun sake komawa bayan saukar da Sarkin Bizantine Maurice, wanda ya haifar da fadace-fadace da yawa kuma daga karshe an sasanta.Yaƙe-yaƙe na Romawa da Farisa sun ƙare da Yaƙin Byzantine-Sasaniya na 602-628, wanda ya ƙare a cikin kewayen Konstantinoful.Daular Sasaniya ta fada hannun Yakin Larabawa a yakin al-Qādisiyyah a shekara ta 632, wanda ke nuna karshen daular.Zamanin Sasaniya, wanda ake ganin yana da tasiri sosai a tarihin Iran, ya yi tasiri sosai ga wayewar duniya.Wannan zamanin ya ga kololuwar al'adun Farisa kuma ya yi tasiri ga wayewar Romawa, inda al'adunsa suka kai yammacin Turai, Afirka,Sin , daIndiya .Ya taka muhimmiyar rawa wajen tsara fasahar Turai da Asiya ta tsakiya.Al'adun daular Sasania sun yi tasiri sosai a duniyar Musulunci, inda suka mayar da mamayar da Musulunci ya yi wa Iran zuwa Renaissance na Farisa.Yawancin abubuwan da suka zama al'adun Musulunci daga baya, ciki har da gine-gine, rubuce-rubuce, da sauran gudunmawa, sun samo asali ne daga Sasaniyawa.