Bayan da Suleiman ya gaji mahaifinsa, ya soma yaƙi da sojoji da yawa, daga ƙarshe ya kai ga tawaye a ƙarƙashin jagorancin Ottoman da ya naɗa gwamnan Damascus a shekara ta 1521. Ba da daɗewa ba Suleiman ya yi shiri don cin Belgrade daga Masarautar Hungary —wani abu ne kakansa. Mehmed na biyu ya kasa cimma nasara saboda karfin tsaron da John Hunyadi ya yi a yankin.Kama shi yana da mahimmanci wajen kawar da Hungarians da Croats waɗanda, bayan cin nasarar Albaniyawa , Bosniak, Bulgarians , Byzantines da Sabiyawa, ya kasance babban ƙarfin da zai iya toshe ƙarin nasarorin Ottoman a Turai.Suleiman ya kewaye birnin Belgrade kuma ya fara tashin bama-bamai daga wani tsibiri na Danube.Belgrade, tare da sansanin maza 700 kawai, kuma ba ta samun taimako daga Hungary, ta fadi a cikin Agusta 1521.