Da yake fuskantarkasar Sin mai karfi a arewa maso gabas da Siam mai tasowa a kudu maso gabas, Sarki Bodawpaya ya juya zuwa yamma don fadadawa.^[72] Ya ci Arakan a cikin 1785, ya mamaye Manipur a cikin 1814, kuma ya kama Assam a 1817-1819, wanda ya kai ga iyaka mara kyau daIndiya ta Burtaniya .An bar magajin Bodawpaya Sarki Bagyidaw don ya kawar da tawayen Birtaniya a Manipur a 1819 da Assam a 1821-1822.Hare-haren wuce gona da iri da 'yan tawaye daga yankunan Birtaniya ke karewa da hare-haren wuce gona da iri da Burma suka yi ya kai ga yakin Anglo-Burmese na farko (1824-26).Tsawon shekaru 2 da kashe fam miliyan 13, Yaƙin Anglo-Burmese na farko shine yaƙi mafi tsayi kuma mafi tsada a tarihin Indiyawan Biritaniya, ^[73] amma ya ƙare da gagarumin nasarar Birtaniyya.Burma ta ba da duk abin da Bodawpaya ya samu na yamma (Arakan, Manipur da Assam) da Tenasserim.An murkushe Burma tsawon shekaru ta hanyar biyan wani babban lamuni na fam miliyan daya (sai dalar Amurka miliyan 5).^{[74 <]} > A cikin 1852, Birtaniya ba tare da izini ba kuma cikin sauƙi sun kwace lardin Pegu a yakin Anglo-Burmese na biyu.Bayan yakin, Sarki Mindon ya yi ƙoƙari ya zamanantar da ƙasar Burma da tattalin arziƙin ƙasar, kuma ya yi yunƙurin yin ciniki da yanki don hana ci gaba da mamayewar Birtaniyya, gami da mikawa Karenni Jihohin Karenni ga Birtaniyya a 1875. Duk da haka, Birtaniyya, sun firgita da haɗin gwiwar Faransanci. Indochina, ya haɗa sauran ƙasar a cikin Yaƙin Anglo-Burmese na Uku a 1885, kuma ya aika da Sarkin Burma na ƙarshe Thibaw da danginsa zuwa gudun hijira a Indiya.