Siege na Sofia ya faru a cikin 1382 ko 1385 a lokacin yakin Bulgarian-Ottoman.Ya kasa kare kasarsa daga hannun Daular Usmaniyya, a shekara ta 1373 Sarkin Bulgeriya Ivan Shishman ya amince ya zama Basaraken Ottoman kuma ya auri 'yar uwarsa Kera Tamara ga Sarkinsu Murad I, yayin da Daular Usmaniyya za ta mayar da wasu sansanonin da aka ci.Duk da zaman lafiya, a farkon shekarun 1380 ne Ottoman suka koma yakin neman zabe tare da kewaye muhimmin birnin Sofia wanda ke kula da manyan hanyoyin sadarwa zuwa Sabiya da Macedonia.Akwai ƙananan bayanai game da kewaye.Bayan yunkurin mamaye birnin na banza, kwamandan Ottoman Lala Shahin Pasha ya yi la'akari da yin watsi da kewayen.Sai dai wani dan kasar Bulgeriya ya yi nasarar jawo gwamnan birnin Ban Yanuka daga kagara don farauta kuma Turkawa sun kama shi.Babu jagora, Bulgarian sun mika wuya.An lalata katangar birnin tare da kafa sansanin Ottoman.Tare da hanyar zuwa arewa maso yamma da aka share, Ottomans sun kara matsawa kuma suka kama Pirot da Niš a 1386, don haka suna tafiya tsakanin Bulgaria da Serbia.