Tawayen Lê Văn Khôi wani muhimmin tawaye ne a cikin karni na 19 na Vietnam, inda kudancin Vietnamese, Katolika na Vietnamese, mishan Katolika na Faransa da kuma mazauna kasar Sin a karkashin jagorancin Lê Văn Khôi sun yi adawa da mulkin Imperial na Emperor Minh Mạng.Yayin da Minh Mạng ya tara sojoji don murkushe tawayen, Lê Văn Khôi ya ƙarfafa kansa a cikin sansanin Saigon kuma ya nemi taimakon Siamese.Rama III, Sarkin Siam, ya karɓi tayin kuma ya aika da sojoji su kai farmaki kan lardunan Ha-tien na Vietnam da An-giang da sojojin daular Vietnam a Laos da Cambodia .Janar Truong Minh Giang ya kori wadannan sojojin Siamese da Vietnam a lokacin rani 1834.An ɗauki shekaru uku don Minh Mạng don kwantar da tawaye da kuma harin Siamese. Rashin nasarar tawayen ya yi mummunar tasiri a kan al'ummomin Kirista na Vietnam.Sabbin tsanantawa ga Kiristoci sun biyo baya, kuma aka bukaci a nemo da kashe sauran masu wa’azi a ƙasashen waje.