An kafa Florida ta Sifen a cikin 1513, lokacin da Juan Ponce de León ya yi iƙirarin yankin Florida naSpain a lokacin balaguron farko na Turai zuwa Arewacin Amurka.An faɗaɗa wannan da'awar yayin da masu bincike da yawa (musamman Pánfilo Narváez da Hernando de Soto) suka sauka a kusa da Tampa Bay a tsakiyar shekarun 1500 kuma suka yi ta yawo har zuwa arewaci zuwa tsaunin Appalachian da kuma zuwa yamma kamar Texas a galibin binciken zinare da bai yi nasara ba.^[14] An kafa presidio na St. Augustine a gabar Tekun Atlantika ta Florida a 1565;An kafa jerin ayyuka a fadin Florida panhandle, Georgia, da South Carolina a lokacin 1600s;kuma Pensacola an kafa shi a yammacin panhandle na Florida a cikin 1698, yana ƙarfafa da'awar Mutanen Espanya ga wannan yanki na yankin.An sami sauƙin sarrafa ikon Mutanen Espanya na tsibirin Florida ta hanyar rugujewar al'adun asali a cikin ƙarni na 17.Ƙungiyoyin 'yan asalin ƙasar Amirka da dama (ciki har da Timucua, Calusa, Tequesta, Apalachee, Tocobaga, da mutanen Ais) sun kasance mazaunan Florida na tsawon lokaci, kuma mafi yawan sun yi tsayayya da kutsawar Mutanen Espanya zuwa ƙasarsu.Duk da haka, rikici da balaguron Spain, hare-haren da ’yan mulkin mallaka na Carolina suka yi da abokansu na asali, da (musamman) cututtuka da aka kawo daga Turai sun haifar da raguwar yawan jama'ar 'yan asalin Florida, kuma manyan yankunan tsibirin sun kasance mafi yawan mutanen da ba su zauna ba. zuwa farkon shekarun 1700.A tsakiyar shekarun 1700, ƙananan ƙungiyoyin Creek da sauran 'yan gudun hijira na Amirkawa sun fara ƙaura zuwa kudu zuwa Florida ta Sipaniya bayan da mazauna Carolina ta Kudu da hare-hare suka tilasta musu barin ƙasarsu.Daga baya ’yan Afirka-Amurka da suka tsere daga bauta a yankunan da ke kusa da su suka shiga tare da su.Waɗannan sabbin shigowa - da wataƙila wasu ƴan tsira daga zuriyar ƴan asalin Florida - a ƙarshe sun haɗa kai zuwa sabuwar al'adar Seminole.