Tun daga lokacin da Sarkin Makidoniya Amyntas na miƙa ƙasarsa ga Farisa a cikin kusan 512-511, Masedoniyawa da Farisa ba baƙi ba ne kuma.Ƙullawar ƙasar Makidoniya wani ɓangare ne na sojojin Farisa da Darius Mai Girma (521-486) ​​ya fara a shekara ta 513—bayan shirye-shirye masu yawa—wani ƙaƙƙarfan sojojin Achaemenid sun mamaye ƙasashen Balkan kuma suka yi ƙoƙari su kayar da Scythians na Turai da ke yawo zuwa arewacin kogin Danube.Mamayewar Farisa ya kai ga hawan Makidoniya a kaikaice kuma Farisa na da wasu bukatu iri daya a yankin Balkan;tare da taimakon Farisa, Macedonia sun tsaya don samun riba mai yawa a kashe wasu kabilun Balkan kamar su Paeonians da Helenawa.Gabaɗaya, mutanen Makidoniya sun kasance "masu son juna da amfani na Farisa. Sojojin Makidoniya sun yi yaƙi da Atina da Sparta a cikin sojojin Xerxes. kuma ga mutanen Makidoniya musamman kamar Yaunã Takabara ko “Girkawa masu huluna masu kama da garkuwa”, wataƙila suna nufin hular Kausia ta Makidoniya.