Bayan Tawayen Mon na 1774 da nasarar Siamese na kame Chiang Mai da ke karkashin Burma a 1775, Sarki Hsinbyushin ya nada Maha Thiha Thura Janar Janar na Yakin Sino-Burmese don gudanar da wani gagarumin farmaki na Arewacin Siam a karshen 1775 domin dakile. Karkashin ikon Siamese karkashin Sarki Taksin na Thonburi.Yayin da sojojin Burma suka zarce na Siamese, hari na tsawon watanni uku na Phitsanulok shine babban yakin.Masu kare Phitsanulok, karkashin jagorancin Chaophraya Chakri da Chaophraya Surasi, sun bijirewa Burma.Yakin dai ya kai ga rashin nasara har sai da Maha Thiha Thura ya yanke shawarar kawo cikas ga layin samar da kayayyaki na Siamese, wanda ya kai ga faduwar Phitsanulok a watan Maris na shekara ta 1776. Burma ta samu galaba amma rasuwar sarki Hsinbyushin ba da dadewa ba ta lalata ayyukan Burma kamar yadda sabon sarkin Burma ya ba da umarnin janyewar. na duk sojojin da suka koma Ava.Ficewar Maha Thiha Thura da wuri daga yaƙi a 1776 ya bar sauran sojojin Burma a Siam don ja da baya cikin rudani.Daga nan sai Sarki Taksin ya yi amfani da wannan damar ya tura wasu Janar dinsa domin su addabi Burma da ke ja da baya.Sojojin Burma sun bar Siam gaba daya a watan Satumba na 1776 kuma yakin ya ƙare.Mamayewar Maha Thiha Thira na Siam a cikin 1775-1776 shine yakin Burma-Siamese mafi girma a lokacin Thonburi.Yaƙin (da yaƙe-yaƙe na gaba) gaba ɗaya ya ruguje kuma ya lalata manyan sassan Siam shekaru da yawa masu zuwa, wasu yankuna ba za su sake zama gaba ɗaya ba har zuwa ƙarshen karni na 19.^[55]