Bayan mutuwar Vasily a 1533, ɗansa da magaji, Ivan IV, yana da shekaru uku kawai.Mahaifiyarsa, Elena Glinskaya, yi aiki a matsayin mai mulki da kuma tsunduma a iko gwagwarmaya da sauran dangi da boyars.Sarkin Yaren mutanen Poland-Lithuania ya yanke shawarar yin amfani da yanayin kuma ya bukaci a dawo da yankunan da Vasily III ya ci.A lokacin rani na 1534, Grand Hetman Jerzy Radziwiłł da Tatars sun lalata yankin Chernigov, Novgorod Severk, Radogoshch, Starodub, da Briansk.A cikin Oktoba 1534, sojojin Muscovite karkashin jagorancin Prince Ovchina-Telepnev-Obolensky, Prince Nikita Obolensky, da Prince Vasily Shuisky suka mamaye Lithuania, suna ci gaba har zuwa Vilnius da Naugardukas, kuma sun gina kagara a tafkin Sebezh a shekara ta gaba, kafin a yi shi. tsaya.Sojojin Lithuania a karkashin Hetman Radziwill, Andrei Nemirovich, Hetman na Poland Jan Tarnowski, da Semen Belsky sun kaddamar da wani gagarumin farmaki inda suka dauki Gomel da Starodub.A shekara ta 1536, sansanin Sebezh ya ci nasara da sojojin Lithuania na Nemirovich lokacin da suka yi ƙoƙari su kewaye shi, sa'an nan kuma Muscovites suka kai hari kan Liubech, sun lalata Vitebsk, suka gina garu a Velizh da Zavoloche.Lithuania da Rasha sun yi shawarwarin tsagaita wuta na tsawon shekaru biyar, ba tare da musayar fursunoni ba, inda Homel ya ci gaba da zama a karkashin ikon sarki, yayin da Muscovy Rus' ya rike Sebezh da Zavoloche.