The First Great Awakening was the nation's first major religious revival, occurring in the middle of the 18th century, and it injected new vigor into Christian faith. It was a wave of religious enthusiasm among Protestants that swept the colonies in the 1730s and 1740s, leaving a permanent impact on American religion. Jonathan Edwards was a key leader and a powerful intellectual in colonial America. George Whitefield came over from England and made many converts.

The Great Awakening emphasized the traditional Reformed virtues of Godly preaching, rudimentary liturgy, and a deep awareness of personal sin and redemption by Christ Jesus, spurred on by powerful preaching that deeply affected listeners. Pulling away from ritual and ceremony, the Great Awakening made religion personal to the average person.

The Awakening had a major impact in reshaping the Congregational, Presbyterian, Dutch Reformed, and German Reformed denominations, and it strengthened the small Baptist and Methodist denominations. It brought Christianity to the slaves and was a powerful event in New England that challenged established authority. It incited rancor and division between the new revivalists and the old traditionalists who insisted on ritual and liturgy. The Awakening had little impact on Anglicans and Quakers.