The leaders of the crusade included John of Brienne, King of Jerusalem, Leopold of Austria, the Grand Masters of the Hospitallers, the Templars and the Teutonic Knights. They held a war council in Acre, with Andrew leading the meeting. In early November, the Crusaders launched a campaign for the Jordan River, forcing Al-Adil I, Sultan of Egypt, to withdraw without fighting; the crusaders then pillaged Beisan. After the crusaders returned to Acre, Andrew did not participate in any other military actions. Instead, he collected relics, including a water jug allegedly used at the marriage at Cana, the heads of Saint Stephen and Margaret the Virgin, the right hands of the Apostles Thomas and Bartholomew and a part of Aaron's rod. If Thomas the Archdeacon's report of certain "evil and audacious men" in Acre who "treacherously passed him a poisoned drink" is reliable, Andrew's inactivity was because of illness.

Andrew decided to return home at the very beginning of 1218, even though Raoul of Merencourt, Latin Patriarch of Jerusalem, threatened him with excommunication. When he arrived in Bulgaria, Andrew was detained until he "gave full surety that his daughter would be united in marriage" to Ivan Asen II of Bulgaria, according to Thomas the Archdeacon. Andrew returned to Hungary in late 1218. Andrew's "crusade had achieved nothing and brought him no honor", according to historian Thomas Van Cleve.