The 1271 siege of Tripoli was initiated by the Mamluk ruler Baibars against the Frankish ruler of the Principality of Antioch and the County of Tripoli, Bohemond VI. It followed the dramatic fall of Antioch in 1268, and was an attempt by the Mamluks to completely destroy the Crusader states of Antioch and Tripoli.

Edward I of England landed in Acre on May 9, 1271, where he was soon joined by Bohemond and his cousin King Hugh of Cyprus and Jerusalem. Baibars accepted Bohemond's offer of a truce in May, abandoned the siege of Tripoli.