After the Mamluk victories over Mongols at Ain Jalut in 1260 and Elbistan in 1277, the Il-khan Abaqa sent his brother Möngke Temur at the head of a large army which numbered about 40–50,000 men, chiefly Armenians under Leo II and Georgians under Demetrius II. On 20 October 1280, the Mongols took Aleppo, pillaging the markets and burning the mosques. The Muslim inhabitants fled for Damascus, where the Mamluk leader Qalawun assembled his forces.

In a pitched battle, the Armenians, Georgians and Oirats under King Leo II and Mongol generals routed and scattered the Mamluk left flank, but the Mamluks personally led by Sultan Qalawun destroyed the Mongol centre. Möngke Temur was wounded and fled, followed by his disorganized army. However, Qalawun chose to not pursue the defeated enemy, and the Armenian-Georgian auxiliaries of the Mongols managed to withdraw safely.