The Battle of the Orontes was fought on 15 September 994 between the Byzantines and their Hamdanid allies under Michael Bourtzes against the forces of the Fatimid vizier of Damascus, the Turkish general Manjutakin. The battle was a Fatimid victory.

Shortly after the battle, the Fatimid caliphate took control of Syria, removing the Hamdanids from power they had held since 890. Manjutakin went on to capture Azaz and continued his siege of Aleppo.