Byzantine Empire Isaurian dynasty

Great Outbreak
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746 Jan 1

Great Outbreak

İstanbul, Turkey

There was a flare-up of bubonic plague between 746-749 CE – referred to as the Great Outbreak – in Constantinople, Greece, and Italy, with a death toll of upwards of 200,000, but in 750 CE the disease seemed to vanish


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Last Updated: : Mon Apr 18 2022