In the 1720s, as the Toungoo Dynasty waned, power shifts in the Lanna region led to Ong Kham, a Tai Lue prince, fleeing to Chiang Mai and later declaring himself its king in 1727. The same year, due to high taxation, Chiang Mai rebelled against the Burmese, successfully repelling their forces in subsequent years. This rebellion led to Lanna's division, with Thipchang becoming the ruler of Lampang, while Chiang Mai and the Ping valley gained independence.^[20]

Thipchang's rule in Lampang lasted until 1759, followed by various power struggles, involving his descendants and Burmese intervention. The Burmese took control of Lampang in 1764 and, following the death of Abaya Kamani, the Burmese governor of Chiang Mai, Thado Mindin took over. He worked on assimilating Lanna into Burmese culture, reducing the power of local Lanna nobles, and used political hostages, like Chaikaew, to ensure loyalty and control over the region.

By the mid-18th century, Chiang Mai once again became a tributary to the emerging Burmese dynasty and faced another rebellion in 1761. This period also saw the Burmese using the Lan Na region as a strategic point for further invasions into Laotian territories and Siam. Despite initial attempts at independence in the early 18th century, Lanna, especially Chiang Mai, faced recurring Burmese invasions. By 1763, after a prolonged siege, Chiang Mai fell to the Burmese, marking another era of Burmese dominion in the region.