The North-West Rebellion was a resistance by the Métis people under Louis Riel and an associated uprising by First Nations Cree and Assiniboine of the District of Saskatchewan against the Canadian government. Many Métis felt that Canada was not protecting their rights, their land, and their survival as a distinct people.

Riel had been invited to lead the movement of protest; he turned it into a military action with a heavily religious tone. That alienated Catholic clergy, whites, most Indigenous tribes, and some Métis, but he had the allegiance of 200 armed Métis, a smaller number of other Indigenous warriors, and at least one white man at Batoche in May 1885, who confronted 900 Canadian militia and some armed local residents. About 91 people would die in the fighting that occurred that spring before the resistance's collapse.

Despite some notable early victories at Duck Lake, Fish Creek, and Cut Knife, the resistance was quashed when overwhelming government forces and a critical shortage of supplies brought about the Métis' defeat in the four-day Battle of Batoche. The remaining Aboriginal allies scattered. Several chiefs were captured, and some served prison time. Eight men were hanged in Canada's largest mass hanging, for murders performed outside the military conflict.

Riel was captured, put on trial, and convicted of treason. Despite many pleas across Canada for clemency, he was hanged. Riel became a heroic martyr to Francophone Canada. That was one cause for the rise of ethnic tensions into a deep division, whose repercussions continue to be felt. The suppression of the conflict contributed to the present reality of the Prairie Provinces being controlled by English speakers, who allowed only a very limited francophone presence, and helped cause the alienation of French Canadians, who were embittered by the repression of their countrymen. The key role that the Canadian Pacific Railway played in transporting troops caused support by the Conservative government to increase, and Parliament authorized funds to complete the country's first transcontinental railway.