Bacon's Rebellion was an armed rebellion held by Virginia settlers that took place from 1676 to 1677. It was led by Nathaniel Bacon against Colonial Governor William Berkeley, after Berkeley refused Bacon's request to drive Native Americans out of Virginia. Thousands of Virginians from all classes (including those in indentured servitude) and races rose up in arms against Berkeley, chasing him from Jamestown and ultimately torching the settlement. The rebellion was first suppressed by a few armed merchant ships from London whose captains sided with Berkeley and the loyalists. Government forces arrived soon after and spent several years defeating pockets of resistance and reforming the colonial government to be once more under direct Crown control.

Bacon's rebellion was the first rebellion in the North American colonies in which discontented frontiersmen took part (a somewhat similar uprising in Maryland involving John Coode and Josias Fendall took place shortly afterward). The alliance between European indentured servants and Africans (a mix of indentured, enslaved, and Free Negroes) disturbed the colonial upper class. They responded by hardening the racial caste of slavery in an attempt to divide the two races from subsequent united uprisings with the passage of the Virginia Slave Codes of 1705. While the rebellion did not succeed in the initial goal of driving the Native Americans from Virginia, it did result in Berkeley being recalled to England.