Franklin suffered from obesity throughout his middle-aged and later years, which resulted in multiple health problems, particularly gout, which worsened as he aged. Benjamin Franklin died from pleuritic attack at his home in Philadelphia on April 17, 1790. He was aged 84 at the time of his death. His last words were reportedly, "a dying man can do nothing easy", to his daughter after she suggested that he change position in bed and lie on his side so he could breathe more easily.

Approximately 20,000 people attended his funeral. He was interred in Christ Church Burial Ground in Philadelphia. Upon learning of his death, the Constitutional Assembly in Revolutionary France entered into a state of mourning for a period of three days, and memorial services were conducted in honor of Franklin throughout the country.