John Wilkes Booth was a well-known actor and a Confederate spy from Maryland; though he never joined the Confederate army, he had contacts with the Confederate secret service. After attending an April 11, 1865 speech in which Lincoln promoted voting rights for blacks, Booth hatched a plot to assassinate the President. When Booth learned of the Lincolns' intent to attend a play with General Grant, he planned to assassinate Lincoln and Grant at Ford's Theatre. Lincoln and his wife attended the play Our American Cousin on the evening of April 14, just five days after the Union victory at the Battle of Appomattox Courthouse. At the last minute, Grant decided to go to New Jersey to visit his children instead of attending the play.

On April 14, 1865, hours before he was assassinated, Lincoln signed legislation establishing the United States Secret Service, and, at 10:15 in the evening, Booth entered the back of Lincoln's theater box, crept up from behind, and fired at the back of Lincoln's head, mortally wounding him. Lincoln's guest, Major Henry Rathbone, momentarily grappled with Booth, but Booth stabbed him and escaped. After being attended by Doctor Charles Leale and two other doctors, Lincoln was taken across the street to Petersen House. After remaining in a coma for eight hours, Lincoln died at 7:22 in the morning on April 15.tanton saluted and said, "Now he belongs to the ages."incoln's body was placed in a flag-wrapped coffin, which was loaded into a hearse and escorted to the White House by Union soldiers. President Johnson was sworn in later that same day.

Two weeks later, Booth, refusing to surrender, was tracked to a farm in Virginia, and was mortally shot by Sergeant Boston Corbett and died on April 26. Secretary of War Stanton had issued orders that Booth be taken alive, so Corbett was initially arrested to be court martialed. After a brief interview, Stanton declared him a patriot and dismissed the charge.